I'm working with an e-client on the freshening-up of her living and dining rooms. She's having crown moulding and built-ins added, and my suggestion is to paint the wall and trim the same color, but with different finishes à la this room by Suzanne Kasler.
...and then, paint the insets of the built-ins with a contrasting color that coordinates with our design scheme...
Nothing radical, but a nice twist, and a step away from traditional. Remember how Martha toned down the heavy (albeit impressive) moulding in one of her myriad homes with this pretty shade of blush? Splendid.
By keeping all this trim monochromatic, the room stays out of Fussydom